Apr 30, 2025 · 1 min read
GEN: CZI Releases TranscriptFormer AI Model — the Cross-Species Cell Atlas

“Hey model, if I prompt you with the marker genes for a cell type, can you complete the transcription factors that you believe would be highly expressed with expression of these genes?” posed Theofanis Karaletsos, head of artificial intelligence at the Chan Zuckerberg Initiative, as he imagined a future where scientists no longer waded through mountains of literature, data and experiments to ask a very pointed biological question.
In conversation with Genetic Engineering & Biotechnology News, he and CZI’s head of science, Steve Quake, share more about our newest AI model, TranscriptFormer, which probes cellular biology across species for therapeutic applications.
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About the Chan Zuckerberg Initiative
The Chan Zuckerberg Initiative was founded in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education, to addressing the needs of our local communities. Our mission is to build a better future for everyone. For more information, please visit chanzuckerberg.com.